Thyroid storm in a refractory hyperthyroid patient: A case report
Kaan Sevgi1, Crystal Guillen1
, Sinan Aran2
1Kansas City University of Medicine & Biosciences, School of Medicine, Kansas City, United States
2Department of Family Medicine, Demiroglu Science University, İstanbul, Türkiye
Keywords: Graves’ disease, hyperthyroidism, multidisciplinary care, plasmapheresis, thyroid storm.
Abstract
Thyroid storm is a rare and life-threatening endocrinological emergency characterized by severe manifestations of thyrotoxicosis and multi-organ involvement. Prompt recognition and early intervention are paramount to reduce the high morbidity and mortality rates associated with this condition. A 45-year-old woman with a history of Graves’ disease presented with high-grade fever, marked tachycardia, confusion, and persistent vomiting. This case report explores a unique presentation of thyroid storm in a hyperthyroid patient refractory to conventional treatment. The report integrates insights from key reviews and guidelines to present a cohesive approach to optimal care.
Cite this article as: Sevgi K, Guillen C, Aran S. Thyroid storm in a refractory hyperthyroid patient: A case report. D J Med Sci 2025;11(2):97-100. doi: 10.5606/fng. btd.2025.172.
The case report's conception and design, data collection, literature review, and manuscript composition were all influenced: K.S.; Provided support in the procurement of data, the interpretation of findings, and the critical revision of the manuscript to address significant intellectual content: C.G.; Provided senior supervision, critical revisions, clinical expertise, and approval of the final manuscript version: S.A. The final manuscript was reviewed and endorsed by all authors, who acknowledge their responsibility for its content.
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
The authors received no financial support for the research and/or authorship of this article.
Data Sharing Statement:
The data that support the findings of this study are available from the corresponding author upon reasonable request.