A rare case of cranial Ewing's sarcoma metastasis developing in a patient with a history of occipital glioma surgery: Case presentation in light of the literature
Ramazan Sari1
, Beyza Nur Yilmaz2, Fatih Han Bolukbasi1, Azat Mustafayev3, İlhan Elmaci1
1Department of Neurosurgery, Demiroğlu Science Universitiy, İstanbul, Türkiye
2Medical Student, University of Health Sciences, Hamidiye Intenational Medical School, İstanbul, Türkiye
3Department of Neurosurgery, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, Türkiye
Keywords: Ewing sarcoma, glioma, metastasis.
Abstract
Ewing sarcoma (ES) is an aggressive small round cell malignancy that rarely involves the cranium, either primarily or metastatically. Its sequential occurrence with glioma in the same patient is exceedingly uncommon. We report a 24-year-old man with a history of tibial and abdominal ES who had previously undergone total resection of a left occipital low-grade glioma. This case highlights the rarity of cranial metastatic ES following occipital glioma and emphasizes the importance of long-term surveillance and consideration of possible underlying biological predisposition.
Cite this article as: Sari R, Yilmaz BN, Bolukbasi FH, Mustafayev A, Elmaci İ. A rare case of cranial Ewing's sarcoma metastasis developing in a patient with a history of occipital glioma surgery: Case presentation in light of the literature. D J Med Sci 2026;12(1):61-68. doi: 10.5606/fng.btd.2026.226.
R.S.: Contributed to the surgical management of the patient, study design, manuscript planning, and editorial revision of the manuscript; B.N.Y.: Contributed to the literature review and manuscript preparation; F.H.B.: Contributed to manuscript supervision, figure preparation, and final revision of the manuscript; A.M.: Contributed to archival data collection and case documentation; ‹.E.: Supervised the clinical management and overall conduct of the study. All authors read and approved the final manuscript.
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
Data Sharing Statement
The data that support the findings of this study are available from the corresponding author upon reasonable request.
The authors received no financial support for the research and/or authorship of this article.
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