A rare case of cranial Ewing's sarcoma metastasis developing in a patient with a history of occipital glioma surgery: Case presentation in light of the literature

Ramazan Sari; Beyza Nur Yilmaz; Fatih Han Bolukbasi; Azat Mustafayev; İlhan Elmaci

doi:10.5606/fng.btd.2026.226

Ramazan Sari¹, Beyza Nur Yilmaz², Fatih Han Bolukbasi¹, Azat Mustafayev³, İlhan Elmaci¹

¹Department of Neurosurgery, Demiroğlu Science Universitiy, İstanbul, Türkiye
²Medical Student, University of Health Sciences, Hamidiye Intenational Medical School, İstanbul, Türkiye
³Department of Neurosurgery, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, Türkiye

Keywords: Ewing sarcoma, glioma, metastasis.

Abstract

Ewing sarcoma (ES) is an aggressive small round cell malignancy that rarely involves the cranium, either primarily or metastatically. Its sequential occurrence with glioma in the same patient is exceedingly uncommon. We report a 24-year-old man with a history of tibial and abdominal ES who had previously undergone total resection of a left occipital low-grade glioma. This case highlights the rarity of cranial metastatic ES following occipital glioma and emphasizes the importance of long-term surveillance and consideration of possible underlying biological predisposition.

Cite this article as: Sari R, Yilmaz BN, Bolukbasi FH, Mustafayev A, Elmaci İ. A rare case of cranial Ewing's sarcoma metastasis developing in a patient with a history of occipital glioma surgery: Case presentation in light of the literature. D J Med Sci 2026;12(1):61-68. doi: 10.5606/fng.btd.2026.226.